State of the Art in Liver Imaging – MR Diffusion/Perfusion

Luis Marti-Bonmati, MD, PhD,1,2 Ángel Alberich-Bayarri, MSc,1 Roberto Sanz-Requena, MSc,1 Javier Sánchez-González3
1 Radiology Department, Quiron Hospital, Valencia, Spain;
2 Radiology Department, Dr. Peset University Hospital, Valencia, Spain;
3 MR Clinical Science Philips Healthcare, Spain


Correspondence to:

Luis Marti-Bonmati, MD, PhD
Radiology Department
Quiron Hospital
Avda Blasco Ibañez 14
46010 Valencia, Spain
e-mail: Luis.Marti@uv.es


Abstract
The purpose of this review is to summarise the role of magnetic resonance (MR) diffusion-weighted (DW) and perfusion-weighted (PW) techniques in liver imaging diagnosis. Both techniques improve the capabilities of MR in the management of both diffuse and focal liver lesions. These techniques allow qualitative analysis based on the semiologic analysis of the signal, and also the extraction of quantifiable features which add to the clinical assessment of the severity, degree of change, or biological status of a disease. The development, standardisation, and optimisation of these DW and PW imaging acquisition protocols and data analyses will change the clinical research and patient care scenarios in the evaluation of the different hepatic diseases.
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