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Susanne C. Ladd is Senior Radiologist at the Department of Diagnostic and Interventional Radiology and Neuroradiology (Director: Professor Michael Forsting) at the University Hospital Essen, Essen, Germany. After studying physics and medicine at the University of Münster, Germany, she received her postgraduate training in general radiology at the University Hospital Zurich and the University Hospital Hannover (Director: Professor Michael Galanski). Her main interests are whole-body screening MRI and, recently, high field MRI.
Whole-body MRI

Susanne C. Ladd
Department of Diagnostic and Interventional Radiology
and Neuroradiology, University Hospital Essen, Essen,
Germany

Address for correspondence:
Susanne C. Ladd MD
Department of Diagnostic and Interventional Radiology
and Neuroradiology, University Hospital Essen
Hufelandstrasse 55, D-45122 Essen, Germany
Tel. +49-201-723-84534 Fax +49-201-723-1548
Email: susanne.ladd@uni-duisburg-essen.de

Abstract
This article discusses recent developments in whole body magnetic resonance imaging (wb-MRI) and its clinical indications. Improvements in hardware, such as extended table translation, and a high number of simultaneous receiver channels are prerequisites for wb-MRI. Generally, two different strategies can be followed: multi-station wb-MRI and data acquisition during continuous table movement, both permitting a variety of different sequences and contrasts.

Wb-MR angiography facilitates the visualisation of the entire arterial system from head to toe with the exception of the coronary arteries. Wb-MRI can replace skeletal scintigraphy in the detection of bone marrow metastases by using fluid-sensitive sequences, while fast contrast-enhanced sequences can be used as an alternative approach in the search for tumours and metastases. Such a wb-MRI approach can even be superior to a combination of positron emission tomography and computer tomography in the detection of distant metastases.

One of the challenges for which the radiologist must be prepared in wb-MR protocols is a dramatic increase in image data, which might result in an increase in false negative findings.

Further developments in wb-MRI aim at multi-contrast imaging and further improvements in coil technology for faster data acquisition (parallel imaging), with the goal of reducing total examination costs.