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| Peter McCullough completed his
medical degree at the University
of Texas Southwestern Medical
School in Dallas, was Resident at
the University of Washington in
Seattle, and gained a cardiology
fellowship at William Beaumont
Hospital in Royal Oak. He earned
a master’s degree in public health
at the University of Michigan
in Ann Arbor. At Beaumont
Hospital, Dr. McCullough leads
an active research team that
focuses on disease prevention
and determinants of cardiorenal
disease, including obesity,
cardiac and renal risk factors,
and novel biomarkers. He has
published over 500 medical
communications, including over
300 peer-reviewed manuscripts
and abstracts. Dr. McCullough is
on the editorial boards of Reviews
in Cardiovascular Medicine and
The American Journal of Kidney
Disease. He is an internationally
recognized authority on the role
of chronic kidney disease as a
cardiovascular risk state. |
CIN Consensus Working Panel: Executive Summary
Peter A McCullough, MD, MPH
Consultant Cardiologist, William Beaumont Hospital,
Michigan, USA
Address for correspondence:
Dr Peter A McCullough, MD, MPH
Consultant Cardiologist
William Beaumont Hospital, Coolidge Highway
Royal Oak, Michigan 48073, USA
Tel: +1-248-655-5929 Fax: +1-248-380-2008
Email: pmccullough@beaumont.edu
Abstract
Radiological and cardiological procedures continue to
rely on the use of iodinated contrast media for the
identification of vascular structures. Contrast-induced
nephropathy (CIN) is an important complication in
the use of iodinated contrast media which accounts
for a significant number of cases of hospital-acquired
renal failure, with adverse effects on prognosis and
healthcare costs. CIN is likely to remain a significant
challenge for clinicians since more patients are likely to
undergo exposure to contrast media in the future and
since the incidence of chronic kidney disease, the major
risk factor for CIN, is increasing. The CIN Consensus
Working Panel is an international multidisciplinary
group convened to address the challenges of CIN.
A total of 4370 references were identified by literature
search (the MEDLINE and EMBASE databases from
1966 to February 2005), of which 865 were considered
potentially relevant. The results of the literature
search were used to compile reviews covering the
epidemiology and pathogenesis of CIN, baseline renal
function measurement, risk assessment, identification
of high-risk patients, contrast medium use and
preventive strategies. In this summary of the work of
the panel, the consensus statements and an algorithm
for the risk stratification and management of contrastinduced
nephropathy are presented.
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