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Peter McCullough completed his medical degree at the University of Texas Southwestern Medical School in Dallas, was Resident at the University of Washington in Seattle, and gained a cardiology fellowship at William Beaumont Hospital in Royal Oak. He earned a master’s degree in public health at the University of Michigan in Ann Arbor. At Beaumont Hospital, Dr. McCullough leads an active research team that focuses on disease prevention and determinants of cardiorenal disease, including obesity, cardiac and renal risk factors, and novel biomarkers. He has published over 500 medical communications, including over 300 peer-reviewed manuscripts and abstracts. Dr. McCullough is on the editorial boards of Reviews in Cardiovascular Medicine and The American Journal of Kidney Disease. He is an internationally recognized authority on the role of chronic kidney disease as a cardiovascular risk state.
CIN Consensus Working Panel: Executive Summary

Peter A McCullough, MD, MPH
Consultant Cardiologist, William Beaumont Hospital, Michigan, USA

Address for correspondence:
Dr Peter A McCullough, MD, MPH
Consultant Cardiologist
William Beaumont Hospital, Coolidge Highway
Royal Oak, Michigan 48073, USA
Tel: +1-248-655-5929 Fax: +1-248-380-2008
Email: pmccullough@beaumont.edu

Abstract
Radiological and cardiological procedures continue to rely on the use of iodinated contrast media for the identification of vascular structures. Contrast-induced nephropathy (CIN) is an important complication in the use of iodinated contrast media which accounts for a significant number of cases of hospital-acquired renal failure, with adverse effects on prognosis and healthcare costs. CIN is likely to remain a significant challenge for clinicians since more patients are likely to undergo exposure to contrast media in the future and since the incidence of chronic kidney disease, the major risk factor for CIN, is increasing. The CIN Consensus Working Panel is an international multidisciplinary group convened to address the challenges of CIN. A total of 4370 references were identified by literature search (the MEDLINE and EMBASE databases from 1966 to February 2005), of which 865 were considered potentially relevant. The results of the literature search were used to compile reviews covering the epidemiology and pathogenesis of CIN, baseline renal function measurement, risk assessment, identification of high-risk patients, contrast medium use and preventive strategies. In this summary of the work of the panel, the consensus statements and an algorithm for the risk stratification and management of contrastinduced nephropathy are presented.