CIN and clinical research: How should we interpret the data?
Author: Donal Reddan and Arif Mutwali
When interpreting clinical papers, it is important that a number of key principles are considered. These include internal validity (the robustness of the conclusions drawn from the study).... Read more...
Gadolinium and NSF
What is fact and what is theory?
Author: Adrian Holden
Since the publication by Grobner and colleagues in 2006 that first suggested the association between gadolinium-based contrast agents (GBCA) and nephrogenic systemic fibrosis (NSF), there have been many articles published on the subject. Read more...
Contrast medium injection protocols for CT angiography
Author: Dominik Fleischmann, MD
As part of a general trend towards non-invasive imaging techniques, the use of CT and MRI is increasing while the use of other radiological investigations is constant or is in decline Read more...
Contrast media and nephrotoxity
Author: Dr BJ Barrett
Contrast-induced nephropathy (CIN), an acute decline in renal function after administration of an iodinated contrast medium, remains an important problem that can prolong hospitalisation, and increase morbidity and mortality. Read more...
How to treat contrast media reactions
Author: Olivier Clement
The following topics are covered in detail in the article:
1) Diagnosis
2) General management
3) Cutaneous symptoms
4) Respiratory symptoms
5) Generalized anaphylactoid reaction
6) Other systemic reactions
7) Before the reaction
8) After the reaction Read more...
CIN Consensus Working Panel: Executive Summary
Author: Peter A McCullough, MD, MPH
Radiological and cardiological procedures continue to
rely on the use of iodinated contrast media for the
identification of vascular structures. Read more...
Screening of renal function prior to administration of iodinated contrast medium
Author: Norbert Lameire
Renal impairment at baseline (estimated glomerular
filtration rate [eGFR] <60 ml/min/1.73 m2) is the most
important risk marker to predict the risk of contrastinduced
nephropathy (CIN) in patients receiving iodinated
contrast media. Read more...
Radiographic contrast media and thrombosis:
the more we know, the more we need to know
Author: Warren K Laskey
The diverse effects of radiographic contrast media (RCM) on virtually all organ systems extend to the haemostatic system. Before the advent of non-ionic RCM, little controversy surrounded these effects, i.e. inhibition of thrombin generation... Read more...
Contrast media-induced nephropathy:
risk assessment and reduction
Author: Fulvio Stacul
Contrast media-induced nephropathy (CIN) is a problem that is often under-recognised in clinical practice. The renal impairment is usually temporary, but in some patients acute renal failure can develop and dialysis may be necessary. Read more...
